Study Details

OVERVIEW

A Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer, Whose Tumors Express PD-L1 (ASCENT-04)

PROTOCOL SUMMARY

The primary objective of this study is to compare the progression-free survival (PFS) between sacituzumab govitecan-hziy (SG) and pembrolizumab versus treatment of physician's choice (TPC) and pembrolizumab in participants with previously untreated, locally advanced inoperable or metastatic triple-negative breast cancer, whose tumors express programmed cell death ligand 1 (PD-L1).

Participation Requirements

Age

18 Years +

Sex

ALL

Healthy Volunteers

Medical Condition

Triple Negative Breast Cancer, PD-L1 Positive

Gender

N/A

Date

July 2022 - February 2027

Study Type

INTERVENTIONAL

Study Phase

PHASE3

Product

Sacituzumab Govitecan-hziy, Pembrolizumab, Paclitaxel, nab-Paclitaxel, Gemcitabine, Carboplatin

Eligibility Information

Inclusion Criteria

Individuals with locally advanced, inoperable, or metastatic triple-negative breast cancer (TNBC) who have not received previous systemic therapy for advanced disease and whose tumors are programmed cell death ligand 1 (PD-L1) positive at screening.
Individuals must have completed treatment for Stage I to III breast cancer, if indicated, and ≥ 6 months must have elapsed between completion of treatment with curative intent and first documented local or distant disease recurrence.
Individuals presenting with de novo metastatic TNBC are eligible for this study.
TNBC status and tumor PD-L1 combined positive score (CPS) will be confirmed centrally on a recent or archival tumor specimen.
Individuals must have measurable disease by computed tomography (CT) or magnetic resonance imaging (MRI) as per Response Evaluation Criteria in Solid Tumors (RECIST) Version 1.1 criteria as evaluated locally.
Eastern Cooperative Oncology Group (ECOG) performance status score of 0 or 1.
Demonstrates adequate organ function
Male and female individuals of childbearing potential who engage in heterosexual intercourse must agree to use protocol-specified method(s) of contraception.
Individuals with HIV must be on antiretroviral therapy (ART) and have a well-controlled HIV infection/disease.

Exclusion Criteria

Positive serum pregnancy test or women who are lactating.
Received prior therapy with an agent directed to another stimulatory or coinhibitory T-cell receptor.
Individuals may not have received systemic anticancer treatment (with the exception of endocrine therapy) within the previous 6 months or radiation therapy within 2 weeks prior to enrollment.
Individuals may not be participating in a study with an investigational agent or investigational device within 4 weeks prior to randomization. Individuals participating in observational studies are eligible.
Have previously received topoisomerase 1 inhibitors or antibody drug conjugates containing a topoisomerase inhibitor.
Have an active second malignancy.
Have active serious infection requiring antibiotics.
Individuals positive for HIV-1 or 2 with a history of Kaposi sarcoma and/or Multicentric Castleman Disease.
Have active hepatitis B virus (HBV) or hepatitis C virus (HCV) infection.
Has an active autoimmune disease that has required systemic treatment in the past 2 years.
Note: Other protocol defined Inclusion/Exclusion criteria may apply.

Locations

Locations (504)

Alaska Oncology and Hematology

Anchorage, Alaska, United States, 99508

Arizona Oncology Associates, PC-Hope,1845 W Orange Grove Rd

Tucson, Arizona, United States, 85704

Arizona Oncology Associates, PC-Hope,2070 W. Rudasill Rd.

Tucson, Arizona, United States, 85704

Arizona Oncology Associates, PC-Hope

Tucson, Arizona, United States, 85711

Arizona Oncology Associates, PC-Hope,1620 West St. Mary's Road

Tucson, Arizona, United States, 85745

Genesis Cancer and Blood Institute

Hot Springs, Arkansas, United States, 71913

Genesis Cancer and Blood Institute,1456 Higdon Ferry Road Suite B.

Hot Springs, Arkansas, United States, 71914

Saint Bernards Medical Center

Jonesboro, Arkansas, United States, 72401

Saint Bernards Medical Center,4000 Linwood Drive

Paragould, Arkansas, United States, 72450

University of California Los Angeles - Jonsson Comprehensive Cancer Center,201 S. Buena Vista Street, Suite 200

Burbank, California, United States, 91505

University of California Irvine Health Chao Family,1640 Newport Blvd

Costa Mesa, California, United States, 92627

City of Hope

Duarte, California, United States, 91010

University of California San Diego Moores Cancer

La Jolla, California, United States, 92093

University of California Los Angeles - Jonsson Comprehensive Cancer Center,24302 Paseo de Valencia, Suite 200

Laguna Hills, California, United States, 91505

Cancer and Blood Specialty Clinic

Los Alamitos, California, United States, 90720

City of Hope,1601 Avocado Ave

Newport, California, United States, 92660

University of California Irvine Health Chao Family

Orange, California, United States, 92868

City of Hope,209 Fair Oaks Ave

Pasadena, California, United States, 91030

University of California Los Angeles - Jonsson Comprehensive Cancer Center,892 Aerovista Place, Suite 240

San Luis Obispo, California, United States, 93401

Sansum Clinic

Santa Barbara, California, United States, 93105

University of California Los Angeles - Jonsson Comprehensive Cancer Center,2020 Santa Monica Blvd, Suite 600

Santa Monica, California, United States, 90404

University of California Los Angeles - Jonsson Comprehensive Cancer Center,2336 Santa Monica, Suites 302 and 304

Santa Monica, California, United States, 90404

University of California Los Angeles - Jonsson Comprehensive Cancer Center

Santa Monica, California, United States, 90404

St. Jude Hospital Yorba dba St. Joseph Heritage Healthcare

Santa Rosa, California, United States, 95403

Sansum Clinic,2040 Viborg Road

Solvang, California, United States, 93463

City of Hope,5215 Torrance Blvd

Torrance, California, United States, 90503

Torrance Memorial Physician Network - Cancer Care

Torrance, California, United States, 90505

City of Hope,1100 San Bernardino Rd

Upland, California, United States, 91786

University of California Los Angeles - Jonsson Comprehensive Cancer Center,1250 La Venta Dr, Suite 100

Westlake Village, California, United States, 91361

Rocky Mountain Cancer Centers,1700 South Potomac Street

Aurora, Colorado, United States, 80012

Rocky Mountain Cancer Centers

Boulder, Colorado, United States, 80303

Rocky Mountain Cancer Centers,2312 N. Nevada Avenue

Colorado Springs, Colorado, United States, 80907

Rocky Mountain Cancer Centers,6031 E. Woodman Rd.

Colorado Springs, Colorado, United States, 80923

Rocky Mountain Cancer Centers,4700 E. Hale Parkway

Denver, Colorado, United States, 80220

Rocky Mountain Cancer Centers,11750 West 2nd Place

Lakewood, Colorado, United States, 80228

Rocky Mountain Cancer Centers,22 West Dry Creek Circle

Littleton, Colorado, United States, 80120

Rocky Mountain Cancer Centers,10107 Ridge Gate Parkway

Lone Tree, Colorado, United States, 80124

Rocky Mountain Cancer Centers,2030 Mountain View Ave Ste 210

Longmont, Colorado, United States, 80124

Rocky Mountain Cancer Centers,3676 Parker Blvd

Pueblo, Colorado, United States, 81008

Rocky Mountain Cancer Centers,525 W. 15th Street

Pueblo, Colorado, United States, 81008

Rocky Mountain Cancer Centers,8820 Huron Street

Thornton, Colorado, United States, 80260

Eastern Connecticut Hematology and Oncology Associates

Norwich, Connecticut, United States, 06360

Advent Health Medical Group

Altamonte Springs, Florida, United States, 32701

SCRI - Florida Cancer Specialists - North Region R,750 Orienta Ave

Altamonte Springs, Florida, United States, 32701

University of Miami - Sylvester Comprehensive Cancer Center,2801 NE 213th St

Aventura, Florida, United States, 33180

Florida Cancer Specialists,9776 Bonita Beach Road Southeast Suite 201 A

Bonita Springs, Florida, United States, 34135

Florida Cancer Specialists,3630 Manatee Avenue West

Bradenton, Florida, United States, 34205

Florida Cancer Specialists,5985 Silver Falls Run

Bradenton, Florida, United States, 34211

SCRI - Florida Cancer Specialists - North Region R,403 S. Kings Ave.

Brandon, Florida, United States, 33511

Florida Cancer Specialists,1030 Commerce Creek Blvd

Cape Coral, Florida, United States, 33909

SCRI - Florida Cancer Specialists - North Region R,3280 McMullen Booth Road

Clearwater, Florida, United States, 33761

University of Miami - Sylvester Comprehensive Cancer Center,5555 Ponce De Leon Blvd

Coral Gables, Florida, United States, 33146

SCRI - Florida Cancer Specialists - West Palm Beach,224 Memorial Medical Parkway, Suite 300

Daytona Beach, Florida, United States, 32117

University of Miami - Sylvester Comprehensive Cancer Center,1192 East Newport Center Drive

Deerfield Beach, Florida, United States, 33442

Florida Cancer Specialists

Fort Myers, Florida, United States, 33901

Florida Cancer Specialists,8981 Colonial Center Drive

Fort Myers, Florida, United States, 33905

Florida Cancer Specialists,8260 Gladiolus Dr

Fort Myers, Florida, United States, 33908

SCRI - Florida Cancer Specialists - North Region R,6420 W. Newberry Road

Gainesville, Florida, United States, 32605

University of Miami - Sylvester Comprehensive Cancer Center,3850 Hollywood Blvd

Hollywood, Florida, United States, 33021

SCRI - Florida Cancer Specialists - North Region R,100 Highland Avenue

Largo, Florida, United States, 33770

SCRI - Florida Cancer Specialists - North Region R,521 North Lecanto Highway

Lecanto, Florida, United States, 34461

University of Miami - Sylvester Comprehensive Cancer Center,1400 NW 12th Ave

Miami, Florida, United States, 33136

University of Miami - Sylvester Comprehensive Cancer Center

Miami, Florida, United States, 33136

University of Miami - Sylvester Comprehensive Cancer Center,8932 S.W. 97 Ave

Miami, Florida, United States, 33176

Florida Cancer Specialists,1100 Goodlette Road

Naples, Florida, United States, 34102

SCRI - Florida Cancer Specialists - North Region R,4945 SW 49th Place

Ocala, Florida, United States, 34474

SCRI - Florida Cancer Specialists - North Region R,2824 Enterprise Rd

Orange City, Florida, United States, 32763

Advent Health Medical Group,2501 North Orange Ave

Orlando, Florida, United States, 32804

SCRI - Florida Cancer Specialists - North Region R,70 W. Gore Street

Orlando, Florida, United States, 32806

University of Miami - Sylvester Comprehensive Cancer Center,8100 SW 10 Street

Plantation, Florida, United States, 33324

Florida Cancer Specialists,22395 Edgewater Drive

Port Charlotte, Florida, United States, 33980

SCRI - Florida Cancer Specialists - North Region R,1201 Fifth Avenue North

Saint Petersburg, Florida, United States, 33705

SCRI - Florida Cancer Specialists - North Region R

Saint Petersburg, Florida, United States, 33705

Florida Cancer Specialists,600 North Cattlemen Road

Sarasota, Florida, United States, 34232

Florida Cancer Specialists,1970 Golf Street

Sarasota, Florida, United States, 34236

SCRI - Florida Cancer Specialists - North Region R,7154 Medical Center Drive

Spring Hill, Florida, United States, 34608

SCRI - Florida Cancer Specialists - West Palm Beach,301 SE Ocean Blvd, Suite 102

Stuart, Florida, United States, 34994

SCRI - Florida Cancer Specialists - North Region R,3402 West Dr. Martin Luther King Jr. Boulevard

Tampa, Florida, United States, 33607

SCRI - Florida Cancer Specialists - North Region R,4100 Waterman Way

Tavares, Florida, United States, 32778

SCRI - Florida Cancer Specialists - North Region R,1400 US Highway 441 N

The Villages, Florida, United States, 32159

SCRI - Florida Cancer Specialists - North Region R,9320 State Road 54

Trinity, Florida, United States, 34655

Florida Cancer Specialists,836 Sunset Lake Blvd

Venice, Florida, United States, 34292

SCRI - Florida Cancer Specialists - West Palm Beach,3730 7th Terrace, Suite 101

Vero Beach, Florida, United States, 32960

SCRI - Florida Cancer Specialists - West Palm Beach,1037 S. State Road 7, Bldg B, Suite 303

Wellington, Florida, United States, 33414

SCRI - Florida Cancer Specialists - West Palm Beach

West Palm Beach, Florida, United States, 33401

SCRI - Florida Cancer Specialists - North Region R,460 N Orlando Ave

Winter Park, Florida, United States, 32789

Northside Hospital,125 King Avenue

Athens, Georgia, United States, 30606

Piedmont Cancer Institute - Atlanta,1267 Hwy 54W

Atlanta, Georgia, United States, 30214

Winship Cancer Institute of Emory University,550 Peachtree St NE

Atlanta, Georgia, United States, 30308

Piedmont Cancer Institute - Atlanta

Atlanta, Georgia, United States, 30318

Winship Cancer Institute of Emory University

Atlanta, Georgia, United States, 30322

Northside Hospital,5670 Peachtree Dunwoody Rd.

Atlanta, Georgia, United States, 30342

Northside Hospital

Atlanta, Georgia, United States, 30342

Winship Cancer Institute of Emory University,5665 Peachtree Dunwoody Road

Atlanta, Georgia, United States, 30342

Northside Hospital,308 Deep South Farm Rd, Suite 200

Blairsville, Georgia, United States, 30512

Northside Hospital,228 Riverstone Dr.

Canton, Georgia, United States, 30114

Northside Hospital,1505 Northside Blvd, Suite 4600

Cumming, Georgia, United States, 30041

Northside Hospital,3855 Pleasant Hill Rd., Suite 480

Duluth, Georgia, United States, 30096

Northside Hospital,308 Coliseum Dr.

Macon, Georgia, United States, 31217

Piedmont Cancer Institute - Atlanta,775 Poplar Road

Newnan, Georgia, United States, 30265

Piedmont Cancer Institute - Atlanta,1240 Eagles Landing Pkwy

Stockbridge, Georgia, United States, 30281

Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Chicago, Illinois, United States, 60611

University of Illinois Hospital and Health Sciences System (Outpatient Cancer Center)

Chicago, Illinois, United States, 60612

Orchard Healthcare Research Inc,2845 North Sheridan Road, 1st Floor

Chicago, Illinois, United States, 60657

Robert H. Lurie Comprehensive Cancer Center of Northwestern University,1 Kish Hospital Drive

DeKalb, Illinois, United States, 60115

Robert H. Lurie Comprehensive Cancer Center of Northwestern University,10 Health Services Drive

DeKalb, Illinois, United States, 60115

Orchard Healthcare Research Inc,800 Austin Street, Suite 360, East Tower

Evanston, Illinois, United States, 60202

Robert H. Lurie Comprehensive Cancer Center of Northwestern University,300 Randall Road

Geneva, Illinois, United States, 60134

Robert H. Lurie Comprehensive Cancer Center of Northwestern University,304 Randall Road

Geneva, Illinois, United States, 60134

Robert H. Lurie Comprehensive Cancer Center of Northwestern University,1000 N. Westmoreland Road

Lake Forest, Illinois, United States, 60045

Orchard Healthcare Research Inc

Skokie, Illinois, United States, 60077

Robert H. Lurie Comprehensive Cancer Center of Northwestern University,4405 Weaver Parkway

Warrenville, Illinois, United States, 25731

Robert H. Lurie Comprehensive Cancer Center of Northwestern University,4455 Weaver Parkway

Warrenville, Illinois, United States, 60555

Robert H. Lurie Comprehensive Cancer Center of Northwestern University,25 N Winfield Road

Winfield, Illinois, United States, 60190

Regulatory Management Only: TRIO-US Central Administration

Fort Wayne, Indiana, United States, 46845

The University of Kansas Cancer Center,2000 Olathe Blvd

Kansas City, Kansas, United States, 66160

The University of Kansas Cancer Center,12200 W. 110th Street

Overland Park, Kansas, United States, 66210

The University of Kansas Cancer Center,10710 Nall Avenue

Overland Park, Kansas, United States, 66211

The University of Kansas Cancer Center,10730 Nall Avenue

Overland Park, Kansas, United States, 66211

The University of Kansas Cancer Center

Westwood, Kansas, United States, 66205

Norton Cancer Institute - Saint Matthews,234 E. Gray Strret

Louisville, Kentucky, United States, 40202

Norton Cancer Institute - Saint Matthews,676 S. Floyd Street

Louisville, Kentucky, United States, 40202

Norton Cancer Institute - Saint Matthews

Louisville, Kentucky, United States, 40207

Norton Cancer Institute - Saint Matthews,4955 Norton Healthcare Blvd

Louisville, Kentucky, United States, 40241

Hematology Oncology Clinic - Baton Rouge

Baton Rouge, Louisiana, United States, 70809

Hematology Oncology Clinic - Baton Rouge,1673 E Mount Please Drive

Zachary, Louisiana, United States, 70791

Cancer Institute Ascension Saint Agnes

Baltimore, Maryland, United States, 21229

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States, 02215

Dana-Farber Cancer Institute

Boston, Massachusetts, United States, 02215

Massachusetts General Hospital

Boston, Massachusetts, United States, 02215

Massachusetts General Hospital,102 Endicott Street

Danvers, Massachusetts, United States, 01923

Massachusetts General Hospital,2014 Washington St

Newton, Massachusetts, United States, 02462

University of Michigan

Ann Arbor, Michigan, United States, 48109

Ascension St. John Hospital

Grosse Pointe Woods, Michigan, United States, 48236

Ascension Providence Hospital Southfield Cancer Center

Southfield, Michigan, United States, 48075

Mayo Clinic

Rochester, Minnesota, United States, 55905

The West Clinic, PLLC dba West Cancer Center,7668 Airways Blvd

Southaven, Mississippi, United States, 38671

The University of Kansas Cancer Center,2750 Clay Edwards Drive

Kansas City, Missouri, United States, 64116

The University of Kansas Cancer Center,8700 North Green Hills Road

Kansas City, Missouri, United States, 64154

The University of Kansas Cancer Center,4881 N.E. Goodview Circle

Lee's Summit, Missouri, United States, 64064

Nebraska Cancer Specialists,2730 W. Faidley Ave

Grand Island, Nebraska, United States, 68803

Nebraska Cancer Specialists,8303 Dodge Street

Omaha, Nebraska, United States, 68114

Nebraska Cancer Specialists

Omaha, Nebraska, United States, 68130

Nebraska Cancer Specialists,611 Fenwick Dr

Papillion, Nebraska, United States, 68046

Comprehensive Cancer Centers of Nevada - Central V,10001 S. Eastern Avenue, Suite 108

Henderson, Nevada, United States, 89052

Comprehensive Cancer Centers of Nevada - Central V,2460 W. Horizon Ridge Parkway

Henderson, Nevada, United States, 89052

Comprehensive Cancer Centers of Nevada - Central V,1501 Wigwam Parkway, Suite 1300

Henderson, Nevada, United States, 89074

Comprehensive Cancer Centers of Nevada - Central V,653 North Town Center Drive, Suite 402

Las Vegas, Nevada, United States, 89144

Comprehensive Cancer Centers of Nevada - Central V,9280 W. Sunset Road Suite 100

Las Vegas, Nevada, United States, 89148

Comprehensive Cancer Centers of Nevada - Central V,7445 Peak Drive

Las Vegas, Nevada, United States, 89169

Comprehensive Cancer Centers of Nevada - Central V

Las Vegas, Nevada, United States, 89169

Summit Medical Group,1 Diamond Hill Road

Berkeley Heights, New Jersey, United States, 07922

Regional Cancer Care Associates - East Brunswick

East Brunswick, New Jersey, United States, 08816

Summit Medical Group

Florham Park, New Jersey, United States, 07932

John Theurer Cancer Center

Hackensack, New Jersey, United States, 07601

Rutgers Cancer Institute of New Jersey,2575 Klockner Road

Hamilton, New Jersey, United States, 08690

Rutgers Cancer Institute of New Jersey,414 Grand Street

Jersey City, New Jersey, United States, 07302

Rutgers Cancer Institute of New Jersey,600 River Avenue

Lakewood, New Jersey, United States, 08701

Rutgers Cancer Institute of New Jersey,94 Old Short Hills Road

Livingston, New Jersey, United States, 07039

Rutgers Cancer Institute of New Jersey,300 Second Ave

Long Branch, New Jersey, United States, 07740

Regional Cancer Care Associates - East Brunswick,9 Centre Drive

Monroe, New Jersey, United States, 08831

Regional Cancer Care Associates - East Brunswick,34-36 Progress Street

New Brunswick, New Jersey, United States, 08820

Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, United States, 08901

Rutgers Cancer Institute of New Jersey,150 Bergen St.

Newark, New Jersey, United States, 07103

Rutgers Cancer Institute of New Jersey,201 Lyons Avenue

Newark, New Jersey, United States, 07112

Regional Cancer Care Associates - East Brunswick,75 Veronica Avenue

Somerset, New Jersey, United States, 08873

Rutgers Cancer Institute of New Jersey,110 Rehill Ave

Somerville, New Jersey, United States, 08876

Rutgers Cancer Institute of New Jersey,99 Highway 37 West

Toms River, New Jersey, United States, 08755

Rutgers Cancer Institute of New Jersey,100 State Route 36

West Long Branch, New Jersey, United States, 07764

New York Cancer & Blood Specialists - Port Jeffers,72 East Main St.

Babylon, New York, United States, 11702

New York Cancer & Blood Specialists - Port Jeffers,12 East 86th St, Suite 4

Bronx, New York, United States, 10028

Montefiore Medical Center - Montefiore Medical Park

Bronx, New York, United States, 10467

New York Cancer & Blood Specialists - Port Jeffers,2330 Eastchester Road, Suite 360

Bronx, New York, United States, 10469

Perlmutter Cancer Center - Manhattan - 34th Street,259 First Street

Mineola, New York, United States, 11501

New York Cancer & Blood Specialists - Port Jeffers,1 Delaware Dr.

New Hyde Park, New York, United States, 11042

Perlmutter Cancer Center - Manhattan - 34th Street

New York, New York, United States, 10016

NYP/Columbia Univeresity Medical Center/Herbert Irving Comprehensive Cancer Center

New York, New York, United States, 10032

New York Cancer & Blood Specialists - Port Jeffers,365 East Main St.

Patchogue, New York, United States, 11772

New York Cancer & Blood Specialists - Port Jeffers,49 Rte. 347, Newconset Hwy

Port Jefferson Station, New York, United States, 11776

New York Cancer & Blood Specialists - Port Jeffers

Port Jefferson Station, New York, United States, 11776

New York Cancer & Blood Specialists - Port Jeffers,1500 Rte, 112, Building 4

Port Jefferson, New York, United States, 11776

New York Cancer & Blood Specialists - Port Jeffers,750 Old County Rd. Suite 4

Riverhead, New York, United States, 11901

The Ohio State University Wexner Medical Center Clinical Laboratories

Columbus, Ohio, United States, 43212

Zangmeister Cancer Center

Columbus, Ohio, United States, 43219

Northwest Cancer Specialists, PC,5050 NE Hoyt St.

Portland, Oregon, United States, 97213

Northwest Cancer Specialists, PC,265 N. Broadway

Portland, Oregon, United States, 97227

Northwest Cancer Specialists, PC

Tigard, Oregon, United States, 97223

Magee-Womens Hospital of UPMC,200 Oxford Drive

Bethel Park, Pennsylvania, United States, 15102

Magee-Womens Hospital of UPMC,3 St. Francis Way

Cranberry Township, Pennsylvania, United States, 16066

Magee-Womens Hospital of UPMC,2500 West 12th Street

Erie, Pennsylvania, United States, 16505

Magee-Womens Hospital of UPMC,201 State Street, 6 Main

Erie, Pennsylvania, United States, 16550

Magee-Womens Hospital of UPMC,200 Village Drive

Greensburg, Pennsylvania, United States, 15601

Magee-Womens Hospital of UPMC,400 Oxford Drive

Monroeville, Pennsylvania, United States, 15146

University of Pennsylvania Abramson Cancer Center

Philadelphia, Pennsylvania, United States, 19104

Magee-Womens Hospital of UPMC,300 Halket Street

Pittsburgh, Pennsylvania, United States, 15213

Magee-Womens Hospital of UPMC

Pittsburgh, Pennsylvania, United States, 15213

Magee-Womens Hospital of UPMC,5115 Centre Avenue

Pittsburgh, Pennsylvania, United States, 15232

Magee-Womens Hospital of UPMC,9100 Babcock Boulevard

Pittsburgh, Pennsylvania, United States, 15237

Magee-Womens Hospital of UPMC,100 Fairfield Dr

Seneca, Pennsylvania, United States, 16346

Magee-Womens Hospital of UPMC,470 Johnson Road

Washington, Pennsylvania, United States, 15301

Magee-Womens Hospital of UPMC,1703 Innovation Drive

York, Pennsylvania, United States, 17408

Rhode Island Hospital

Providence, Rhode Island, United States, 02903

Rhode Island Hospital,164 Summit Ave, Fain 275A

Providence, Rhode Island, United States, 02906

Tennessee Oncology, PLLC,103 Natchez Park Drive

Dickson, Tennessee, United States, 37055

Tennessee Oncology, PLLC,4488 Carothers Parkway

Franklin, Tennessee, United States, 37067

Tennessee Oncology, PLLC,225 Big Station Camp Blvd

Gallatin, Tennessee, United States, 37066

The West Clinic, PLLC dba West Cancer Center

Germantown, Tennessee, United States, 38138

Tennessee Oncology, PLLC,353 New Shackle Island Road

Hendersonville, Tennessee, United States, 37075

Tennessee Oncology, PLLC,5653 First Blvd.

Hermitage, Tennessee, United States, 37076

Tennessee Oncology, PLLC,103 Physicians Way

Lebanon, Tennessee, United States, 37090

Tennessee Oncology, PLLC,1840 Medical Center Parkway

Murfreesboro, Tennessee, United States, 37129

Tennessee Oncology, PLLC,2004 Hayes Street

Nashville, Tennessee, United States, 37203

Tennessee Oncology, PLLC,SCRI Oncology Partners

Nashville, Tennessee, United States, 37203

Tennessee Oncology, PLLC

Nashville, Tennessee, United States, 37203

Tennessee Oncology, PLLC,4220 Harding Rd

Nashville, Tennessee, United States, 37205

Tennessee Oncology, PLLC,3443 Dickerson Road

Nashville, Tennessee, United States, 37207

Tennessee Oncology, PLLC,397 Wallace Road

Nashville, Tennessee, United States, 37211

Tennessee Oncology, PLLC,120 Frank Martin Road

Shelbyville, Tennessee, United States, 37160

Tennessee Oncology, PLLC,300 Stonecrest Blvd

Smyrna, Tennessee, United States, 37167

The Center for Cancer and Blood Disorders - Magnolia,515 W. Mayfield Rd.

Arlington, Texas, United States, 76104

Texas Oncology-Austin,901 West 38th Street

Austin, Texas, United States, 78705

Texas Oncology-Austin

Austin, Texas, United States, 78731

Texas Oncology-Austin,4101 James Casey, Suite 100

Austin, Texas, United States, 78745

The Center for Cancer and Blood Disorders - Magnolia,11805 South Freeway

Burleson, Texas, United States, 76028

Texas Oncology-Baylor Charles A. Sammons Cancer Center

Dallas, Texas, United States, 75246

Texas Oncology-Denison

Denison, Texas, United States, 75020

The Center for Cancer and Blood Disorders - Magnolia

Fort Worth, Texas, United States, 76104

Oncology Consultants,1631 North Loop West

Houston, Texas, United States, 77008

Oncology Consultants,925 Gessner

Houston, Texas, United States, 77024

Oncology Consultants

Houston, Texas, United States, 77030

University of Texas MD Anderson Cancer Center,1155 Pressler St

Houston, Texas, United States, 77030

University of Texas MD Anderson Cancer Center

Houston, Texas, United States, 77030

Mays Cancer Center

San Antonio, Texas, United States, 78229

The Center for Cancer and Blood Disorders - Magnolia,920 Santa Fe Drive

Weatherford, Texas, United States, 76086

Huntsman Cancer Institute, University of Utah,165 North University Avenue

Farmington, Utah, United States, 84025

Huntsman Cancer Institute, University of Utah,1280 E. Stringham Avenue

Salt Lake City, Utah, United States, 84106

Huntsman Cancer Institute, University of Utah

Salt Lake City, Utah, United States, 84112

Huntsman Cancer Institute, University of Utah,5126 West Daybreak Parkway

South Jordan, Utah, United States, 84009

Virginia Oncology Associates,744 N. Battlefield Blvd

Chesapeake, Virginia, United States, 23320

Virginia Cancer Institute,7501 Right Flank Road

Mechanicsville, Virginia, United States, 23116

Virginia Oncology Associates,1051 Loftis Blvd Suite 100

Newport News, Virginia, United States, 23606

Virginia Oncology Associates

Norfolk, Virginia, United States, 23502

Virginia Cancer Institute,210 Medical Park Boulevard

Petersburg, Virginia, United States, 23805

Virginia Cancer Institute,1401 Johnston-Willis Drive

Richmond, Virginia, United States, 23235

Virginia Cancer Institute

Richmond, Virginia, United States, 23298

Virginia Oncology Associates,1950 Glenn Mitchell Drive

Virginia Beach, Virginia, United States, 23456

Northwest Cancer Specialists, PC,210 SE 136th Avenue

Vancouver, Washington, United States, 98684

Hospital Británico de Buenos Aires

Buenos Aires, Argentina, 1426

Instituto de Oncología Ángel H. Roffo

Caba, Argentina, 1417

Fundacion CORI para la Investigacioy y Prevención del Cancer

Capital, Argentina, F5300COE

Instituto de Oncologia de Rosario

Rosario, Argentina, 2000

CAIPO Centro Para La Atención Integral Del Pacient

San Miguel de Tucumán, Argentina, 4000

Clinica Viedma

Viedma, Argentina, 8500

Border Medical Oncology

Albury, New South Wales, Australia, 2640

Saint George Hospital - Australia

Kogarah, New South Wales, Australia, 2217

Mater Hospital - North Sydney

North Sydney, New South Wales, Australia, 2060

GenesisCare - North Shore

St Leonards, New South Wales, Australia, 2065

Mater Misericordiae Limited and Mater Research Limited

South Brisbane, Queensland, Australia, 4101

Princess Alexandra Hospital

Woolloongabba, Queensland, Australia, 4102

Cancer Research SA (CRSA)

Adelaide, South Australia, Australia, 5000

Icon Cancer Centre Hobart

Hobart, Tasmania, Australia, 7000

Monash Medical Centre

Clayton, Victoria, Australia, 3168

Austin Hospital

Melbourne, Victoria, Australia, 3084

Peter MacCallum Cancer Centre

Parkville, Victoria, Australia, 3050

Breast Cancer Research Center - Western Australia

Nedlands, Western Australia, Australia, 6009

Medizinische Universität Innsbruck

Innsbruck, Austria, 06020

Ordensklinikum Linz GmbH Barmherzige Schwestern

Linz, Austria, 4010

Landeskrankenhaus Salzburg

Salzburg, Austria, A-5020

Universitätsklinikum Sankt Pölten

Sankt Poelten, Austria, 3100

Medizinische Universität Wien

Wien, Austria, 1090

Institut Jules Bordet

Anderlecht, Belgium, 1070

Algemeen Ziekenhuis Klina

Brasschaat, Belgium, 2930

Cliniques Universitaires Saint-Luc

Brussels, Belgium, 1200

Universitair Ziekenhuis Brussel

Brussels, Belgium

Grand Hopital de Charleroi - Notre Dame

Charleroi, Belgium, 6000

Universitair Ziekenhuis Gent

Gent, Belgium, 9000

UZ Leuven

Leuven, Belgium, 3000

Centre Hospitalier Universitaire Université Cathol

Namur, Belgium, 5000

Hospital Araújo Jorge - Associacao de Combate ao Cancer em Goias - ACCG

Goiânia, Brazil, 74605-070

Centro de Pesquisa Clinica Em Oncologia - ONCOSITE

Ijui, Brazil, 98700-000

Hospital de Clinicas de Porto Alegre - HCPA

Itajai, Brazil, 88301-220

Centro de Pesquisas Clinicas da Fundacao Doutor Amaral Carvalho - Hospital Amarval Carvalho

Jau, Brazil, 17210080

Associacao Hosptialar Moinos de Vento - Hospital Moinhos de Vento

Porto Alegre, Brazil, 90035-00

Hospital de Clínicas de Porto Alegre

Porto Alegre, Brazil, 90035-903

Hospital Sao Lucas da PUCRS

Porto Alegre, Brazil, 90610001

Instituto Nacional de Câncer - Brazil

Rio de Janeiro, Brazil

Núcleo de Oncologia da Bahia

Salvador, Brazil, 40170170

CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia - Centro Universitário FMABC

Santo Andre, Brazil, 09060-650

Real e Benemerita Associacao Portuguesa de Beneficencia - Hospital Beneficencia Portuguesa (BP) - Unidade Paulista

São Paulo, Brazil, 01323-001

Clinica de Pesquisas e Centro de Estudos em Oncolo

São Paulo, Brazil, 1317000

Fundação Pio XII - Hospital de Câncer de Barretos

São Paulo, Brazil, 14784400

Nucleo de Pesquisa Clinica da Rede Sao Camilo

São Paulo, Brazil, 4014002

Tom Baker Cancer Centre

Calgary, Canada, T2N 5G2

Cross Cancer Institute

Edmonton, Canada, T6G 1Z2

QEII Health Sciences Centre

Halifax, Canada, B3H 1V7

Grand River Regional Cancer Centre at Grand River Hospital

Kitchener, Canada, N2G 1G3

London Health Sciences Centre

London, Canada, N6A 5W9

McGill University Health Centre

Montreal, Canada, H4A 3J1

Jewish General Hospital

Montréal, Canada, H3T 1E2

Princess Margaret Cancer Centre - University Health Network

Ontario, Canada, M5G 2M9

Ottawa Hospital - General Campus

Ottawa, Canada, K1H 8L6

Sunnybrook Research Institute

Toronto, Canada, M4N 3M5

Mount Sinai Hospital

Toronto, Canada, M5G 1X5

British Columbia Cancer - Vancouver

Vancouver, Canada, V5Z 4E6

Oncovida - Santiago

Providencia, Chile, 7510035

Clínica IRAM

Santiago DE CHILE, Chile

Centro de Cancer Pontificia Universidad Catolica

Santiago Region, Chile, 8330032

Clínica Alemana

Santiago, Chile, 7630000

James Lind Centro de Investigacion del Cancer

Temuco, Chile

Masarykuv Onkologicky Ustav, Klinika Komplexni Onkologicke Pece

Brno, Czechia, 65653

Fakultní Thomayerova nemocnice

Hradec Kralove, Czechia, 50005

Fakultní Nemocnice Hradec Králové

Hradec Králové, Czechia, 500 05

Fakultni nemocnice Olomouc, Onkologicka klinika

Olomouc, Czechia, 77520

Vseobecna Fakultni Nemocnice v Praze, Onkologicka klinika

Prague, Czechia, 12808

Fakultní Nemocnice Královské Vinohrady, Radioterapeuticka a onkologicka klinika

Praha, Czechia, 100 34

Sainte Catherine Institut du Cancer Avignon Provence

Avignon, France, 84918

Centre Hospitalier Régional et Universitaire de Be

Besancon, France, 25030

Polyclinique Bordeaux Nord Aquitaine

Bordeaux, France, 33000

Hôpital Morvan, Institut de cancérologie

Brest, France, 29200

Centre de Lutte contre le Cancer - François Bacles

Caen, France, 14000

Centre Jean Perrin

Clermont Ferrand, France, 63011

Centre Leon Berard

Lyon, France, 69373

Institut Paoli-Calmettes

Marseille CEDEX 9, France, 13273

Institut Régional du Cancer de Montpellier

Montpellier Cedex 5, France, 34298

Centre de Cancérologie du Grand Montpellier

Montpellier, France, 34070

Hôpital Privé du Confluent

Nantes, France, 44202

Hospices Civils de Lyon, Hôpital Lyon Sud

Pierre-Benite, France, 69495

Centre Armoricain de Radiothérapie, dImagerie Méd

Plerin, France, 22190

Centre Eugène Marquis

Rennes Cedex, France, 35042

Institut Claudius Regaud - IUCT-O

Toulouse, France

Institut Gustave Roussy

Villejuif, France, 94800

Helios Klinikum Berlin-Buch

Berlin, Germany, 13125

: Gynakologisches Zentrum Bonn, Schwerpunkt Gyn. Onkologie,

Bonn, Germany, 53111

Marienhospital Bottrop

Bottrop, Germany, 46236

Universitätsklinikum Erlangen, Frauen klinik

Erlangen, Germany, 91054

Kliniken Essen-Mitte - Evangelische Huyssens-Stift

Essen, Germany, 45136

Praxis für interdisziplinäre Onkologie & Hämatolog

Freiburg, Germany, 79110

: Universitätsklinikum Hamburg-Eppendorf

Hamburg, Germany, 20246

Facharztzentrum Eppendorf

Hamburg, Germany, 20249

Nationales Centrum für Tumorerkrankungen

Heidelberg, Germany, 69120

Klinik Frauenheilkunde, Uniklinik ClO, Studienzentrale

Köln, Germany, 50937

Universitätsklinikum Schleswig-Holstein Institut fur Klinische Chermie

Lübeck, Germany, 23538

Universitatsklinikum Mannheim GmBH, Frauenklinik

Mannheim, Germany, 68167

Universitätsklinikum Münster, Bereich Senologie an der klinik fur Frauenheilkunde und Gerburtschilfe

Munster, Germany, 48149

EV. Krankenhaus Bethesda - Johanniter GmbH, Station 1 Brustzentrum Niederrhein

Mönchengladbach, Germany, 41061

Rotkreuzklinikum Munchen Frauenklinik

München, Germany, 80637

Klinik und Poliklinik für Frauenheilkunde

München, Germany, 81675

Universitatsklinikum Tubingen

Tübingen, Germany, 72076

St. Josefs-Hospital Wiesbaden GmbH, Gynakologie und Geburtshilfe

Wiesbaden, Germany, 65189

Department of Medicine, Queen Mary Hospital

Hong Kong, Hong Kong

Hong Kong Sanatorium and Hospital

Hong Kong, Hong Kong

Tuen Mun Hospital

Hong Kong, Hong Kong

Prince of Wales Hospital - Hong Kong

New Territories, Hong Kong

Orszagos Onkologiai Intezet

Budapest, Hungary, 1122

Uzsoki Utcai Kórház

Budapest, Hungary, 1145

Debreceni Egyetem Klinikai Központ

Debrecen, Hungary, 4032

Petz Aladár Egyetemi Oktató Kórház - Gy?r

Gyor, Hungary, 9024

Soroka Medical Center

Beer-Sheva, Israel, 8410101

Rambam Health Care Campus

Haifa, Israel, 3109601

Shaare Zedek Medical Center

Jerusalem, Israel, 9103102

Hadassah - Hebrew University Medical Center

Jerusalem, Israel

Meir Medical Center

Kfar Saba, Israel, 4428164

Rabin Medical Center

Petah Tikva, Israel, 4941492

Kaplan Medical Center

Rehovot, Israel, 7661041

Sheba Medical Center Hospital - Tel Hashomer

Tel Aviv, Israel, 52621

Tel Aviv Sourasky Medical Center

Tel Aviv, Israel, 64239

IRCCS Istituto Tumori "Giovanni Paolo II"

Bari, Italy, 70124

SSD Oncologia Medica Addarii-Zamagni, IRCSS Azienda Ospedaliero-Universitaria di Bologna - Policlinico di Sant'Orsola

Bologna, Italy

UO Oncologia, ASST degli Spedali Civili di Brescia

Brescia, Italy, 25123

IRCCS Ospedale Policlinico San Martino

Genova GE, Italy, 16132

S.C. Oncologia medica, ASST di Lecco

Lecco, Italy, 23900

Presidio Ospedaliero di Lucca

Lucca, Italy, 55100

Ospedale Generale Provinciale - Macerata

Macerata, Italy, 62100

Ospedale San Raffaele

Milano, Italy, 20132

Fondazione IRCCS - Istituto Nazionale dei Tumori

Milano, Italy, 20133

Istituto Europeo di Oncologia

Milan, Italy, 20141

Centro Ricerca Fase I, Fondazione IRCSS San Gerado dei Tintori

Monza, Italy, 20090

AOU "Luigi Vanvitelli"

Napoli, Italy, 80131

Oncologia Medica Senologica Sperimentale - Istituto Nazionale Tumori IRCCS Fondazione G. Pascale

Napoli, Italy, 80131

AOU Maggiore della Carita

Novara, Italy, 28100

Istituto Oncologico Veneto - IRCCS

Padova, Italy, 35128

S.O.C Oncologia Medica, Nuovo Ospedale di Prato Santo Stefano

Prato, Italy, 59100

Policlinico di Roma

Roma, Italy, 00161

Fondazione Policlinico Universitario Agostino Geme

Rome, Italy, 00168

Azienda Ospedaliera Universitaria Senese - Losped

Siena, Italy, 53100

Aichi Cancer Center Hospital

Aichi, Japan, 464-8681

Tohoku University Hospital

Aoba-ku, Japan, 980-8574

Juntendo University Hospital

Bunkyo-ku, Japan, 113-8431

Chiba Cancer Center

Chuo-ku, Japan, 260-8717

Osaka Prefectural Hospital Organization Osaka International Cancer Institute

Chuo-ku, Japan, 541-8567

NHO Shikoku Cancer Center

Ehime, Japan, 791-0280

Fukushima Medical University Hospital

Fukushima, Japan

Saitama Cancer Center

Inamachi, Japan, 362-0806

Hakuaikai Sagara Hospital

Kagoshima-shi, Japan, 892-0833

Tokai University Hospital

Kanagawa, Japan, 259-1193

National Cancer Center Hospital East

Kashiwa, Japan, 277-8577

The Cancer Institute Hospital of JFCR

Koto-ku, Japan, 135-8550

Kumamoto University Hospital

Kumamoto- shi, Japan, 860-8556

Kure Medical Center And Chugoku Cancer Center

Kure, Japan, 737-0023

Mie University Hospital

Mie, Japan, 514-8507

Nagoya University Hospital

Nagoya, Japan, 466-8560

Nagoya City University Hospital

Nagoya, Japan, 467-8602

Hiroshima City Hiroshima Citizens Hospital

Naka-ku, Japan, 730-8518

NIigata Cancer Center Hospital

Niigata-shi, Japan, 951-8566

Okayama University Hospital

Okayama, Japan, 700-8558

Gunma Prefectural Cancer Center

Ota, Japan, 373-8550

Kyoto University Hospital

Sakyo-ku, Japan, 606-8507

Hokkaido Cancer Center

Sapporo, Japan, 003-0804

Shizuoka General Hospital

Shizuoka-city, Japan, 420-8527

Shizuoka Cancer Center

Shizuoka, Japan, 411-8777

Osaka University Hospital

Suita, Japan, 565-0871

Showa University Hospital

Tokyo, Japan, 142-8555

Kanagawa Cancer Center

Yokohama, Japan, 241-8515

National Cancer Center - Korea

Goyang-si Gyeonggi-do, Korea, Republic of, 10408

Seoul National University Bundang Hospital

Seongnam-si, Korea, Republic of, 13620

Severance Hospital

Seoul, Korea, Republic of, 03722

Asan Medical Center

Seoul, Korea, Republic of, 05505

Samsung Medical Center

Seoul, Korea, Republic of, 06351

Korea University Anam Hospital

Seoul, Korea, Republic of, 2841

Seoul National University Hospital

Seoul, Korea, Republic of, 3080

The Catholic University of Korea, Seoul St. Mary's Hospital

Seoul, Korea, Republic of, 6591

Hospital Pulau Pinang

Georgetown, Malaysia, 10450

Hospital Sultan Ismail

Johor Bahru, Malaysia, 81100

Hospital Kuala Lumpur

Kuala Lumpur, Malaysia, 47500

Pantai Hospital Kuala Lumpur

Kuala Lumpur, Malaysia, 59100

University Malaya Medical Centre (UMMC)

Kuala Lumpur, Malaysia, 59100

Institut Kanser Negara

Putrajaya, Malaysia, 62250

Hospital Wanita dan Kanak-Kanak Sabah

Sabah, Malaysia, 88996

Sarawak General Hospital

Sarawak, Malaysia, 93586

Icaro Investigaciones en Medicina S.A. de C.V.

Chihuahua, Mexico, 31000

Cryptex Investigación Clínica

Ciudad de Mexico, Mexico, 06100

Centro para el Desarrollo de la Medicina

Culiacan, Mexico, 80230

Panamerican Clinical Research Mexico - Guadalajara

Guadalajara, Mexico, 44670

Medical Care and Research S.A. de C.V

Merida, Mexico, 97070

Avix Investigacion Clinica S.C.

Monterrey, Mexico, 64710

Fucam A.C.

México, Mexico, 4980

Oncológico Potosino

San Luis Potosi, Mexico, 78209

FAICIC Clínical Research

Veracruz, Mexico, 91900

iBiomed - Investigacion Biomedica para el Desarrol

Zapopan, Mexico, 45070

Amphia Ziekenhuis - Breda Langendijk

Breda, Netherlands, 4818 CK

Universitair Medisch Centrum Groningen

Groningen, Netherlands, 9700 RB

Medisch Centrum Leeuwarden

Leeuwarden, Netherlands, 8934 AD

Erasmus Medisch Centrum

Rotterdam, Netherlands

Uniwersyteckie Centrum Kliniczne, Klinika Onkologii i Radioterapii

Gdansk, Poland, 80-952

Narodowy Instytut Onkologii im. Marii Sklodowskiej

Gliwice, Poland, 44-102

SP ZOZ Opolskie Centrum Onkologii im. prof. Tadeusza Koszarowskiego

Opole, Poland, 45-061

Wielkopolskie Centrum Onkologii im. Marii Sklodowskiej-Curie

Poznan, Poland, 61- 866

Mazowiecki Szpital Wojewódzki im. w. Jana Pawa II w

Siedlce, Poland, 08-110

Wojskowy Instytut Medyczny

Warsaw, Poland, 04-141

Narodowy Instytut Onkologii im.Marii Marii Sklodowskiejs

Warszawa, Poland, 02-781

Ponce Medical School Foundation Inc.

Ponce, Puerto Rico, 00716

Hopelands Cancer Centre

Hilton, South Africa, 3245

The Medical Oncology Centre of Rosebank

Johannesburg, South Africa, 2196

University of Pretoria

Pretoria, South Africa, 0002

Hospital Teresa Herrera - Materno Infantil

A Coruña, Spain, 15006

Hospital Universitari Dexeus

Barcelona, Spain, 08028

Hospital Clinic Barcelona

Barcelona, Spain, 08036

Hospital Clínic de Barcelona

Barcelona, Spain, 08036

Hospital de la Santa Creu i Sant Pau

Barcelona, Spain, 8023

Hospital Universitari Vall d'Hebrón

Barcelona, Spain, 8035

Hospital Universitario de Basurto

Bilbo, Spain, 48013

Hospital Universitari Arnau de Vilanova

Lleida, Spain, 25198

Hospital General Universitario Gregorio Marañón

Madrid, Spain, 28007

MD Anderson Cancer Centre Madrid

Madrid, Spain, 28033

Hospital Universitario Fundación Jiménez Díaz

Madrid, Spain, 28040

Hospital Universitario Virgen de la Victoria

Malaga, Spain, 29010

Hospital General Universitario Morales Meseguer

Murcia, Spain, 30008

Hospital Unviersitario Virgen del Rocio

Sevilla, Spain, 41013

Hospital Universitario Virgen Macarena

Sevilla, Spain, 41071

Hospital Universitario de Canarias

Tenerife, Spain, 38320

Hospital Clínico Universitario de Valencia

Valencia, Spain, 46010

Kantonsspital Baden

Baden, Switzerland, 5404

Kantonsspital Baselland - Standort Liestal

Liestal, Switzerland, 4410

Kantonsspital Sankt Gallen

St. Gallen, Switzerland, 9007

Kantonsspital Winterthur

Winterthur, Switzerland, 8401

Brust-Zentrum Zurich

Zürich, Switzerland, 8008

Changhua Christian Hospital

Changhua, Taiwan, 50006

Kaohsiung Medical University Chung-Ho Memorial Hospital

Kaohsiung, Taiwan, 807

Taipei Medical University-Shuang Ho Hospital

New Taipei City, Taiwan, 235

Chi Mei Hospital, Liouying

Tainan City, Taiwan, 73657

National Cheng Kung University Hospital

Tainan, Taiwan, 704

Taipei Veterans General Hospital

Taipei City, Taiwan, 11217

National Taiwan University Hospital

Taipei, Taiwan, 100

Linkou Chang Gung Memorial Hospital

Taoyuan, Taiwan, 333

Baskent Uni. Dr Turgut Noyan Uyg. ve Aras. Merkezi

Adana, Turkey, 1120

Ankara Il Saglik Mudurlugu SBU Gulhane Egitim Ve A

Ankara, Turkey, 6010

Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

Ankara, Turkey, 6200

Memorial Ankara Hastanesi

Ankara, Turkey, 6520

Hacettepe Üniversitesi Hastanesi

Ankara, Turkey

Trakya Universitesi Tip Fakultesi Hastanesi

Edirne, Turkey, 22030

Istanbul Il Saglik Mudurlugu Goztepe Prof. Dr. Sul

Istanbul, Turkey, 34000

Medipol Mega Universite Hastanesi

Istanbul, Turkey, 34214

Ege Universitesi Hastanesi

Izmir, Turkey, 35100

Medicana International Izmir Hastanesi

İzmir, Turkey, 35575

Acibadem Maslak Hastanesi

Sariyer, Turkey

VKV Amerikan Hastanesi

Sisli, Turkey, 34365

NHS Lothian

Edinburgh, United Kingdom, EH4 2XU

Clinical Trials Unit Lvl 0 Cancer Research UK Beatson Institute

Glasgow, United Kingdom, G12 0YN

Leeds Teaching Hospitals NHS Trust

Leeds, United Kingdom, LS9 7TF

: Barts Health NHS Trust, St Hospital

London, United Kingdom, EC1M 6BQ

Royal Free London NHS Foundation Trust

London, United Kingdom, NW2 2QG

Guy's and Saint Thomas' NHS Foundation Trust

London, United Kingdom, SE1 9RT

University College London Hospitals

London, United Kingdom, WC1E 6BT

Nottingham University Hospitals NHS Trust

Nottingham, United Kingdom, NG5 1PB

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer (ASCENT-04)

OVERVIEW

PROTOCOL SUMMARY

Participation Requirements

Eligibility Information

Inclusion Criteria

Exclusion Criteria

Locations

Locations (504)

Alaska Oncology and Hematology

Arizona Oncology Associates, PC-Hope,1845 W Orange Grove Rd

Arizona Oncology Associates, PC-Hope,2070 W. Rudasill Rd.

Arizona Oncology Associates, PC-Hope

Arizona Oncology Associates, PC-Hope,1620 West St. Mary's Road

Genesis Cancer and Blood Institute

Genesis Cancer and Blood Institute,1456 Higdon Ferry Road Suite B.

Saint Bernards Medical Center

Saint Bernards Medical Center,4000 Linwood Drive

University of California Los Angeles - Jonsson Comprehensive Cancer Center,201 S. Buena Vista Street, Suite 200

University of California Irvine Health Chao Family,1640 Newport Blvd

City of Hope

University of California San Diego Moores Cancer

University of California Los Angeles - Jonsson Comprehensive Cancer Center,24302 Paseo de Valencia, Suite 200

Cancer and Blood Specialty Clinic

City of Hope,1601 Avocado Ave

University of California Irvine Health Chao Family

City of Hope,209 Fair Oaks Ave

University of California Los Angeles - Jonsson Comprehensive Cancer Center,892 Aerovista Place, Suite 240

Sansum Clinic

University of California Los Angeles - Jonsson Comprehensive Cancer Center,2020 Santa Monica Blvd, Suite 600

University of California Los Angeles - Jonsson Comprehensive Cancer Center,2336 Santa Monica, Suites 302 and 304

University of California Los Angeles - Jonsson Comprehensive Cancer Center

St. Jude Hospital Yorba dba St. Joseph Heritage Healthcare

Sansum Clinic,2040 Viborg Road

City of Hope,5215 Torrance Blvd

Torrance Memorial Physician Network - Cancer Care

City of Hope,1100 San Bernardino Rd

University of California Los Angeles - Jonsson Comprehensive Cancer Center,1250 La Venta Dr, Suite 100

Rocky Mountain Cancer Centers,1700 South Potomac Street

Rocky Mountain Cancer Centers

Rocky Mountain Cancer Centers,2312 N. Nevada Avenue

Rocky Mountain Cancer Centers,6031 E. Woodman Rd.

Rocky Mountain Cancer Centers,4700 E. Hale Parkway

Rocky Mountain Cancer Centers,11750 West 2nd Place

Rocky Mountain Cancer Centers,22 West Dry Creek Circle

Rocky Mountain Cancer Centers,10107 Ridge Gate Parkway

Rocky Mountain Cancer Centers,2030 Mountain View Ave Ste 210

Rocky Mountain Cancer Centers,3676 Parker Blvd

Rocky Mountain Cancer Centers,525 W. 15th Street

Rocky Mountain Cancer Centers,8820 Huron Street

Eastern Connecticut Hematology and Oncology Associates

Advent Health Medical Group

SCRI - Florida Cancer Specialists - North Region R,750 Orienta Ave

University of Miami - Sylvester Comprehensive Cancer Center,2801 NE 213th St

Florida Cancer Specialists,9776 Bonita Beach Road Southeast Suite 201 A

Florida Cancer Specialists,3630 Manatee Avenue West

Florida Cancer Specialists,5985 Silver Falls Run

SCRI - Florida Cancer Specialists - North Region R,403 S. Kings Ave.

Florida Cancer Specialists,1030 Commerce Creek Blvd

SCRI - Florida Cancer Specialists - North Region R,3280 McMullen Booth Road

University of Miami - Sylvester Comprehensive Cancer Center,5555 Ponce De Leon Blvd

SCRI - Florida Cancer Specialists - West Palm Beach,224 Memorial Medical Parkway, Suite 300

University of Miami - Sylvester Comprehensive Cancer Center,1192 East Newport Center Drive

Florida Cancer Specialists

Florida Cancer Specialists,8981 Colonial Center Drive

Florida Cancer Specialists,8260 Gladiolus Dr

SCRI - Florida Cancer Specialists - North Region R,6420 W. Newberry Road

University of Miami - Sylvester Comprehensive Cancer Center,3850 Hollywood Blvd

SCRI - Florida Cancer Specialists - North Region R,100 Highland Avenue

SCRI - Florida Cancer Specialists - North Region R,521 North Lecanto Highway

University of Miami - Sylvester Comprehensive Cancer Center,1400 NW 12th Ave

University of Miami - Sylvester Comprehensive Cancer Center

University of Miami - Sylvester Comprehensive Cancer Center,8932 S.W. 97 Ave

Florida Cancer Specialists,1100 Goodlette Road

SCRI - Florida Cancer Specialists - North Region R,4945 SW 49th Place

SCRI - Florida Cancer Specialists - North Region R,2824 Enterprise Rd

Advent Health Medical Group,2501 North Orange Ave

SCRI - Florida Cancer Specialists - North Region R,70 W. Gore Street

University of Miami - Sylvester Comprehensive Cancer Center,8100 SW 10 Street